The beginning of the new millennium marked the meteoric rise of China in a decades-old world order dominated by the United States of America. This book explores the intricacies of China's political, economic and diplomatic relationship with the US and its consequences on international politics. It looks at the historical evolution of the US-China relationship, their struggle for strategic power in various regions of the world, as well as their bilateral involvement. The volume focuses on the need for greater Sino-American political and strategic partnerships in order to address global concerns such as non-proliferation of arms and nuclear weapons, climate change, energy security and international terrorism. It also looks at China's growing influence, the Belt and Road initiative and areas of conflicts and mutual interest. The authors unravel the major conflicts and political developments between the two countries offering a deeper insight into the challenges and strategies for greater co-operation and resolution of differences in the coming decades. This book will be of great interest for researchers and scholars of international relations, China studies, comparative politics, development studies and public policy. It will also be useful for think tanks, policy makers and general readers interested in the USA-China relationship.