Third Generation Egfr Inhibitors by Harun M. Patel, Paperback | Indigo Chapters
Third Generation Egfr Inhibitors by Harun M. Patel, Paperback | Indigo Chapters

Coles

Third Generation Egfr Inhibitors by Harun M. Patel, Paperback | Indigo Chapters

From Harun M. Patel

Current price: $296.50
Loading Inventory...

Size: 1 x 9 x 1

Visit retailer's website
*Product information may vary - to confirm product availability, pricing, and additional information please contact Coles
Third Generation EGFR Inhibitors: Overcoming EGFR Resistance and Toxicity Problemsreviews current issues relating to the design of reversible and irreversible third generation EGFR inhibitors, highlighting the types of mutation responsible for resistance, and providing different chemical starting points for researchers to optimize and develop in designing the next generation of drugs. Beginning with an introduction to EGFR inhibitors and a review of inhibitors currently approved or in clinical trials, the book goes on to discuss current approaches in the development of both covalent irreversible and covalent reversible EGFR Inhibitors. In addition, mechanisms of resistance to third generation inhibitors, and discovery of fourth generation allosteric C797S inhibitors are explored before a discussion of potential future trends. This comprehensive coverage of the design and development of improved analogues to overcome the problems of resistance and toxicity associated with third generation EGFR inhibitors makesThird Generation EGFR Inhibitorsa crucial resource for medicinal chemists, drug developers, and researchers investigating cancer therapeutics. Includes full synthetic schemes of all approved and in-trial third generation inhibitorsHighlights the emergence of fourth generation EGFR inhibitors and the possibilities of them overcoming constraints of third generation compoundsProvides a structural correlation of third and fourth generation EGFR inhibitors, reviewing both their design strategies and typical anticancer activity | Third Generation Egfr Inhibitors by Harun M. Patel, Paperback | Indigo Chapters

More About Coles at Bramalea City Centre

Making Connections. Creating Experiences. We exist to add a little joy to our customers’ lives, each time they interact with us.

Powered by Adeptmind