This handbook focuses on the dynamic nature of global migration and its implications for international business. Migration shapes the societal and organizational contexts of international business; yet studies on migration have only recently become more prominent. For example, the existence of multinational enterprises (MNEs) depends to no small extent on the mobility of people; MNEs source, develop, deploy, and utilize global talent. This talent pool includes, but is not limited to, skilled expatriates or corporate migrants, as well as culturally and ethnically diverse workforces comprised of first- and second-generation migrants, highly skilled refugees that help organizations enhance their legitimacy in host countries, and returnee immigrants encouraged by changing home country conditions. Additionally, global events such as the COVID-19 pandemic and Brexit have introduced new and far-reaching challenges for international firms in managing their international workforces and international mobility. Meanwhile, at the individual level, these issues are compounded for migrants having to cope with multiple work and non-work demands. Chapters in this handbook offer both firm and migrant perspectives, covering topics such as diaspora networks in international alliances, migrant careers, and migrant re-entry issues, among others. Arranged in five sections, this handbook covers the whole spectrum of issues, thus furthering our understanding of this increasingly important topic.