The proceedings volume presents selected papers from the International Conference on Sustainability in Software Engineering & Business Information Management: Innovation & Applications (SSEBIM 2022) held in Olten, Switzerland from September 23-24, 2022. It includes research related to sustainability from both a business and technical point of view. From a business perspective, it not only addresses how to make the business operations more sustainable, but also considers factors such as human values, ethics, environment and responsibility of the businesses. From the technical perspective of software development companies, it focuses on sustainability in software engineering ranging from practices, tools, techniques and methods. The contributions reflect how software engineering teams exhibited pro-activeness in their approaches to lead to sustainable development of the software that is of highest quality and reliability.It is intended for a broad audience, including students, researchers and practitioners who work in software engineering and business information management fields.