This volume details methods to detect Rhinovirus (RV) in clinical samples, propagation and purification of virus, in vivo and in vitro model systems, and the newer molecular tools that are useful for the studying the RV infection and pathogenesis.  Chapters guide readers through a greater of understanding of RV pathogenesis in COPD, childhood asthma development and protective innate immunity.  However, there is much to learn about RV infection in order to develop therapies to treat asthma and COPD exacerbations, prevent development of asthma and treat common colds.  Written in the highly successful  Methods in Molecular Biology  series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Rhinovirus : Methods and Protocols  aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.