Receptor Tyrosine Kinases by Deric L. Wheeler, Hardcover | Indigo Chapters

Receptor tyrosine kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases, and over the last decade they became theNumber 1targets of cancer drugs. Receptor Tyrosine Kinase: Structure, Functions and Role in Human Diseasesystematically covers, for the first time, the shared structural and functional features of the RTK family. Understanding the evolutionary origin of the 58 RTKs, their roles in invertebrates and in human, as well as downstream signaling pathways, is essential for fundamental research and for attempts to develop pharmacological agents able to enhance or intercept their actions. The assembly of chapters written by experts underscores commonalities and is an ideal companion volume toThe Receptor Tyrosine Kinase Family, which refers to specific subfamilies of RTKs, along with their unique landmarks. | Receptor Tyrosine Kinases by Deric L. Wheeler, Hardcover | Indigo Chapters