Very-large-scale integration (VLSI) is the procedure of making an integrated circuit by joining several transistors into a single chip. This book presents an overview on current developments in design nanometer VLSI chips. The vital information described in this book discusses frequently encountered complications and challenges covering significant topics such as novel post-silicon devices, GPU-based parallel computing, design tools, antenna design and rising 3D integration. The book covers the following major aspects of VLSI Design: 3D integrated circuits design for 1000-core processors, Algorithms for CAD tools VLSI design, VLSI design for multi-sensor smart systems on a chip, multilevel mimetic algorithm for large SAT-encoded complications and Parallel symbolic analysis of large analog circuits on GPU platforms.