The book is a collection of papers presented at First Doctoral Symposium on Natural Computing Research (DSNCR 2020), held during 8 August 2020 in Pune, India. The book covers different topics of applied and natural computing methods having applications in physical sciences and engineering. The book focuses on computer vision and applications, soft computing, security for Internet of Things, security in heterogeneous networks, signal processing, intelligent transportation system, VLSI design and embedded systems, privacy and confidentiality, big data and cloud computing, bioinformatics and systems biology, remote healthcare, software security, mobile and pervasive computing, biometrics-based authentication, natural language processing, analysis and verification techniques, large scale networking, distributed systems, digital forensics, and human-computer interaction.