Whitehead was among the first initiates into the 20th century's new cosmological story. This book bring's Whitehead's philosophy of organism into conversation with several components of contemporary scientific cosmology?including relativistic, quantum, evolutionary, and complexity theories?in order to both exemplify the inadequacy of the traditional materialistic-mechanistic metaphysical interpretation of them, and to display the relevance of Whitehead's cosmological scheme to the transdisciplinary project of integrating these theories and their data with the presuppositions of human civilization. This data is nearly crying aloud for a cosmologically ensouled interpretation, one in which, for example, physics and chemistry are no longer considered to be descriptions of the meaningless motion of molecules to which biology is ultimately reducible, but rather themselves become studies of living organization at ecological scales other than the biological.