Nisim Hair & Scalp AnaGain Original Extract - 240ml Best for Normal to Oily Hair/Scalp The Extract is a leave-in application that should be MASSAGED into the scalp twice a day and used with the Nisim Shampoos. The Extract is a leave-in application and is MASSAGED into the scalp twice a day. Nisim does not rely on chemical irritants that cause skin irritation for vasodilation. Natural vasodilation occurs when the product is massaged into the scalp. The Extracts must be used in conjunction with the NewHair Biofactors Shampoo, the extracts are not a stand alone product. The extract works best when it is applied to clean scalp/hair. When you have achieved the desired results (typically 18-24 months) you can discontinue the use of the Extract and maintain your healthy hair using only the NewHair Biofactors Shampoo. This is not a product you have to use for the rest of your life. Nisim’s Original Extract now with AnaGain™ Nisim’s Original Formula Hair and Scalp Extract now includes AnaGain™. AnaGain™ is based on organic pea sprouts designed to stimulate specific signal molecules in the dermal papilla required to reactivate hair growth. Thanks to its composition, AnaGain™ successfully offers a sustainable and novel approach to fight hair loss. In a clinical study involving AnaGain™ it was shown that the anagen: telogen coefficient (proportion of active hair follicles to degenerating ones) could be improved from 4 to 7.2 corresponding to a 78% increase in hair growth in just 3 months. AnaGain™ is thus a natural and sustainable contributor to fuller and thicker hair.