This book highlights the emerging paradigm of nanomedicine, intersecting two burgeoning fields of nanotechnology and medicine. Numerous publications have appeared in the literature over the years, especially in cancer nanomedicine. In a boarder sense, nanomedicine aims to apply the knowledge and tools of nanotechnology in a mission to diagnose early and prevent or treat diseases using biocompatible nanoparticles (NPs). Current research in nanomedicine and its prospects depend on creating new breakthroughs at the nexus of nanomaterials and biological systems, making use of non-toxic NPs and nano/biomaterials as smart theranostic systems for a variety of diseases including cancer, neurodegenerative, orthopedic, and cardiac diseases.  This book provides a review on recent advancements of nanomedicine in the aforementioned emerging areas of nanomedicine.