This book constitutes the refereed proceedings of the 8th International Conference on Modelling and Development of Intelligent Systems, MDIS 2022, held in Sibiu, Romania, during October 28-30, 2022.The 21 papers included in this book were carefully reviewed and selected from 48 submissions. They were organized in the following topical sections as follows: intelligent systems for decision support; machine learning; mathematical models for development of intelligent systems; and modelling and optimization of dynamic systems.