Solving the problem of the negative impact of science and technology on society and the environment is indeed the greatest challenge of our time. To date, this challenge has been taken up by few professional philosophers of science, making this volume a welcome contribution to the general debate. Agazzi’s treatment involves viewing modern science and technology as each constituting systems. Against the background of this approach, he provides a penetrating analysis of science, technology and ethics, and their interrelations. Agazzi sees the solution to the problem as lying in the moral sphere and including a multilateral assumption of responsibility on the part of decision makers both within and outside of science.