Domain theory is a rich interdisciplinary area at the intersection of logic, computer science, and mathematics. This volume contains selected papers presented at the International Symposium on Domain Theory which took place in Shanghai in October 1999. Topics of papers range from the encounters between topology and domain theory, sober spaces, Lawson topology, real number computability and continuous functionals to fuzzy modelling, logic programming, and pi-calculi. This book is a valuable reference for researchers and students interested in this rapidly developing area of theoretical computer science.