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Cd4+cd25+ Regulatory T Cells by B. Kyewski, Paperback | Indigo Chapters
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Cd4+cd25+ Regulatory T Cells by B. Kyewski, Paperback | Indigo Chapters
From B. Kyewski
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yetwehopethatitwillofferinspirationandorientationtothescientistwho wouldliketoenterthis?eld. To date, many different cells have been described that can suppress + + other cells of the immune system: CD4 CD25 regulatory T cells (Treg), + ? CD4 CD25 regulatory T cells, T regulatory 1 cells (Tr1), T-helper 3 cells + ? (Th3),CD8 CD28 Tcells, NKTcells, aswellastolerogenicdendriticcells. Suppressive CD4 T cells fall at least into two categories. So called natural VI Preface + + CD4 CD25 Tregformpartoftheintra-thymicallyselectedTcellrepertoire andapparentlyconstituteadistinctlineage. Incontrast,"adaptive"regulatory Tcellsareinstructedintheperipherytobecomesuppressivecells, theyform + + amoreheterogeneousgroupincludingCD4 CD25 Treg, Tr1, andTh3cells. As natural Treg are so far the best characterized entity, the ?rst three contributionsofthisvolume(C. Cozzoetal. ,C. -S. Hsiehetal. ,andL. | Cd4+cd25+ Regulatory T Cells by B. Kyewski, Paperback | Indigo Chapters